Non-biased enrichment does not improve quantitative proteomic delineation of reovirus T3D-infected HeLa cell protein alterations
Mass spectrometry-based methods have allowed elucidation of alterations in complex proteomes, such as eukaryotic cells.Such studies have identified and measured relative abundances of thousands of host proteins after cells are infected with a virus.One of the potential limitations in such studies is that generally only the most abundant proteins ar